Small frames or windows that can't be resized will force your users to endlessly scroll down in order to view the content on the page. Even worse is placing content so that visitors must scroll left and right to view.
Your users can access the same functions through the main menu bar even after you've disabled it. All you're doing by disabling the right click button is forcing them to use other methods to accomplish the same thing.
Background music can make a page load slowly and if you don't give users a way to turn it off it can really be annoying. Use the rule: if you need an "Off Button" it probably shouldn't be on.
Return customers will be forced to go through your clever intro every time they enter your site and it's not going to seem so clever every time they come to your site and re-view the intro.
There are better ways of advertising than loading up on pop-up windows that open when users view and leave your site. Opening a pop-up only for specific purposes, not just when a user clicks links on your site.
